Drug Target Ontology

Last uploaded: February 15, 2018
Preferred Name

Epidermal growth factor receptor

Synonyms
Definitions

epidermal growth factor receptor (EGFR(L747-E749del, A750P)) with mutation L747-E749del and P750 in EGFR(L747-E749del, A750P) in a nonphosphorylated state epidermal growth factor receptor (EGFR(L861Q)) with mutation Q861 in EGFR(L861Q) in a nonphosphorylated state epidermal growth factor receptor (EGFR(S752-I759del)) with mutation S752-I759del in EGFR(S752-I759del) in a nonphosphorylated state epidermal growth factor receptor (EGFR(G719C)) with mutation C719 in EGFR(G719C) in a nonphosphorylated state epidermal growth factor receptor (EGFR(E746-A750del)) with mutation A746-A750del in EGFR(E746-A750del) in a nonphosphorylated state An epidermal growth factor receptor that is encoded in the genome of human. [PRO:DNx, UniProtKB:P00533] epidermal growth factor receptor (EGFR(L747-T751del,Sins)) with mutation T747-T751del and Silenced in EGFR(L747-T751del,Sins) in a nonphosphorylated state epidermal growth factor receptor (EGFR(L747-S752del, P753S)) with mutation L747-S752del and S753 in EGFR(L747-S752del, P753S) in a nonphosphorylated state epidermal growth factor receptor (EGFR(G719S)) with mutation S719 in EGFR(G719S) in a nonphosphorylated state epidermal growth factor receptor (EGFR(T790M)) with mutation M790 in EGFR(T790M) in a nonphosphorylated state epidermal growth factor receptor (EGFR(L858R)) with mutation R858 in EGFR(L858R) in a nonphosphorylated state epidermal growth factor receptor (EGFR(L858R,T790M)) with mutation R858 and M790 in EGFR(L858R,T790M) in a nonphosphorylated state epidermal growth factor receptor (EGFR) with no mutation in a nonphosphorylated state

ID

http://www.drugtargetontology.org/dto/DTO_03100124

definition

epidermal growth factor receptor (EGFR(L747-E749del, A750P)) with mutation L747-E749del and P750 in EGFR(L747-E749del, A750P) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(L861Q)) with mutation Q861 in EGFR(L861Q) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(S752-I759del)) with mutation S752-I759del in EGFR(S752-I759del) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(G719C)) with mutation C719 in EGFR(G719C) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(E746-A750del)) with mutation A746-A750del in EGFR(E746-A750del) in a nonphosphorylated state

An epidermal growth factor receptor that is encoded in the genome of human. [PRO:DNx, UniProtKB:P00533]

epidermal growth factor receptor (EGFR(L747-T751del,Sins)) with mutation T747-T751del and Silenced in EGFR(L747-T751del,Sins) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(L747-S752del, P753S)) with mutation L747-S752del and S753 in EGFR(L747-S752del, P753S) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(G719S)) with mutation S719 in EGFR(G719S) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(T790M)) with mutation M790 in EGFR(T790M) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(L858R)) with mutation R858 in EGFR(L858R) in a nonphosphorylated state

epidermal growth factor receptor (EGFR(L858R,T790M)) with mutation R858 and M790 in EGFR(L858R,T790M) in a nonphosphorylated state

epidermal growth factor receptor (EGFR) with no mutation in a nonphosphorylated state

geneSymbol

EGFR

geneSynonym

ERBB

ERBB1

HER1

hasDbXref

https://pharos.nih.gov/idg/targets/P00533

label

Epidermal growth factor receptor

prefixIRI

dto:DTO_03100124

prefLabel

Epidermal growth factor receptor

uniprot_xref

P00533

subClassOf

http://www.drugtargetontology.org/dto/DTO_03300152

Delete Subject Author Type Created
No notes to display

This ontology integrates with OntoloBridge, allowing community users to suggest additions to the public ontology. Complete the template below to submit a term request directly to the ontology maintainer.

Term Label (required)
Suggested term name. If a term can be described with multiple synonyms, only list the preferred name here.

Term description (required)
A brief definition, description, or usage of your suggested term. Additional term synonyms may be listed in this section.

Superclass (required)
The parent term of the suggested term. The parent term should be an existing entry of the current ontology. The superclass can be selected directly from Bioportal's Classes tree viewer.

References (optional)
Provide evidence for the existence of the requested term such as Pubmed IDs of papers or links to other resources that describe the term.

Justification (optional)
Provide any additional information about the requested term here.

Request New Term